Version 5.4
Bos taurus Protein: CXCL12
Summary
InnateDB Protein IDBP-683620.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CXCL12
Protein Name stromal cell-derived factor 1
Synonyms SDF1;
Species Bos taurus
Ensembl Protein ENSBTAP00000031235
InnateDB Gene IDBG-632037 (CXCL12)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008009 chemokine activity
GO:0042379 chemokine receptor binding
GO:0045236 CXCR chemokine receptor binding
Biological Process
GO:0001569 patterning of blood vessels
GO:0001667 ameboidal cell migration
GO:0006955 immune response
GO:0007281 germ cell development
GO:0007420 brain development
GO:0008045 motor neuron axon guidance
GO:0008354 germ cell migration
GO:0030334 regulation of cell migration
GO:0030335 positive regulation of cell migration
GO:0042098 T cell proliferation
GO:0045785 positive regulation of cell adhesion
GO:0050930 induction of positive chemotaxis
GO:0060326 cell chemotaxis
GO:0070098 chemokine-mediated signaling pathway
GO:0090026 positive regulation of monocyte chemotaxis
GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:2000107 negative regulation of leukocyte apoptotic process
GO:2000406 positive regulation of T cell migration
Cellular Component
GO:0005576 extracellular region
GO:0009897 external side of plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001811 Chemokine interleukin-8-like domain
PFAM PF00048
PRINTS
PIRSF
SMART SM00199
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q0P5I9
UniProt Splice Variant
Entrez Gene 613811
UniGene Bt.105169
RefSeq NP_001106645
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC119979 DAAA02062252
GenPept AAI19980

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca