InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TNFRSF1B

Summary

InnateDB Protein

IDBP-683975.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TNFRSF1B

Protein Name

tumor necrosis factor receptor superfamily member 1B

Synonyms

TNF-RII/TNFRSF1B;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000034614

InnateDB Gene

IDBG-632369 (TNFRSF1B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 99 interaction(s) predicted by orthology.

Predicted by orthology
Total	99 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005031	tumor necrosis factor-activated receptor activity
GO:0005515	protein binding
GO:0031625	ubiquitin protein ligase binding

Biological Process

GO:0006954	inflammatory response
GO:0007166	cell surface receptor signaling pathway
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
GO:0050728	negative regulation of inflammatory response
GO:0050779	RNA destabilization
GO:0051044	positive regulation of membrane protein ectodomain proteolysis
GO:0071222	cellular response to lipopolysaccharide
GO:0097191	extrinsic apoptotic signaling pathway

Cellular Component

GO:0016020	membrane
GO:0045121	membrane raft

Protein Structure and Domains

PDB ID

InterPro

IPR001368 TNFR/NGFR cysteine-rich region
IPR020411 Tumour necrosis factor receptor 1B

PFAM

PF00020

PRINTS

PR01919

PIRSF

SMART

SM00208

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3MHI9

UniProt Splice Variant

Entrez Gene

338033

UniGene

Bt.67402

RefSeq

NP_001035580

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AF031589 BC105222 DAAA02042944 DAAA02042945

GenPept

AAB84301 AAI05223