Version 5.4
Bos taurus Protein: BT.105088
Summary
InnateDB Protein IDBP-683991.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.105088
Protein Name Dihydrolipoyl dehydrogenase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000033696
InnateDB Gene IDBG-632271 (BT.105088)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004148 dihydrolipoyl dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0006508 proteolysis
GO:0007369 gastrulation
GO:0008033 tRNA processing
GO:0042391 regulation of membrane potential
GO:0045454 cell redox homeostasis
GO:0048240 sperm capacitation
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005929 cilium
GO:0043159 acrosomal matrix
Protein Structure and Domains
PDB ID
InterPro IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II
IPR000815 Mercuric reductase
IPR001327 Pyridine nucleotide-disulphide oxidoreductase, NAD-binding domain
IPR002218 Glucose-inhibited division protein A-related
IPR003953 FAD binding domain
IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IPR006258 Dihydrolipoamide dehydrogenase
IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase
IPR016156 FAD/NAD-linked reductase, dimerisation domain
IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain
PFAM PF00070
PF01134
PF00890
PF02852
PF07992
PRINTS PR00469
PR00945
PR00368
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N206
UniProt Splice Variant
Entrez Gene 533910
UniGene Bt.105088
RefSeq NP_001193099
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02010596
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca