Version 5.4
Bos taurus Protein: TNFRSF21
Summary
InnateDB Protein IDBP-683998.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNFRSF21
Protein Name tumor necrosis factor receptor superfamily member 21
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000026719
InnateDB Gene IDBG-632394 (TNFRSF21)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001783 B cell apoptotic process
GO:0002250 adaptive immune response
GO:0006915 apoptotic process
GO:0006959 humoral immune response
GO:0007165 signal transduction
GO:0030889 negative regulation of B cell proliferation
GO:0031642 negative regulation of myelination
GO:0042130 negative regulation of T cell proliferation
GO:0042552 myelination
GO:0048713 regulation of oligodendrocyte differentiation
GO:0050852 T cell receptor signaling pathway
GO:0051402 neuron apoptotic process
GO:0071356 cellular response to tumor necrosis factor
GO:0097252 oligodendrocyte apoptotic process
GO:2000663 negative regulation of interleukin-5 secretion
GO:2000666 negative regulation of interleukin-13 secretion
GO:2001180 negative regulation of interleukin-10 secretion
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0030424 axon
GO:0031226 intrinsic component of plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR000488 Death domain
IPR001368 TNFR/NGFR cysteine-rich region
IPR011029 Death-like domain
IPR022330 Tumour necrosis factor receptor 21
PFAM PF00531
PF00020
PRINTS PR01971
PIRSF
SMART SM00005
SM00208
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q08DN1
UniProt Splice Variant
Entrez Gene 537922
UniGene Bt.89076
RefSeq NP_001070379
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123657 DAAA02055176 DAAA02055177 DAAA02055178 DAAA02055179
GenPept AAI23658

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca