Version 5.4
Bos taurus Protein: PDCD6
Summary
InnateDB Protein IDBP-684221.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDCD6
Protein Name programmed cell death 6
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000055204
InnateDB Gene IDBG-632598 (PDCD6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.
Predicted by orthology
Total 41 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0046983 protein dimerization activity
GO:0048306 calcium-dependent protein binding
GO:0060090 binding, bridging
Biological Process
GO:0001938 positive regulation of endothelial cell proliferation
GO:0006508 proteolysis
GO:0006886 intracellular protein transport
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010595 positive regulation of endothelial cell migration
GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032007 negative regulation of TOR signaling
GO:0034605 cellular response to heat
GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway
GO:0045766 positive regulation of angiogenesis
GO:0051592 response to calcium ion
GO:0051898 negative regulation of protein kinase B signaling
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0031410 cytoplasmic vesicle
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q1LZ81
UniProt Splice Variant
Entrez Gene 100125927
UniGene
RefSeq NP_001098967
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC116154 DAAA02051474
GenPept AAI16155

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca