InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PFKM

Summary

InnateDB Protein

IDBP-684562.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PFKM

Protein Name

6-phosphofructokinase, muscle type

Synonyms

ATP-PFK; PFK-M;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000000359

InnateDB Gene

IDBG-632886 (PFKM)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003824	catalytic activity
GO:0003872	6-phosphofructokinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008022	protein C-terminus binding
GO:0008443	phosphofructokinase activity
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0019900	kinase binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding
GO:0070061	fructose binding

Biological Process

GO:0006002	fructose 6-phosphate metabolic process
GO:0006096	glycolytic process
GO:0008152	metabolic process
GO:0016310	phosphorylation
GO:0032024	positive regulation of insulin secretion
GO:0042593	glucose homeostasis
GO:0046716	muscle cell cellular homeostasis
GO:0046835	carbohydrate phosphorylation
GO:0051259	protein oligomerization

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005945	6-phosphofructokinase complex
GO:0016324	apical plasma membrane
GO:0070062	extracellular vesicular exosome
GO:0097228	sperm principal piece

Protein Structure and Domains

PDB ID

InterPro

IPR000023 Phosphofructokinase domain
IPR009161 6-phosphofructokinase, eukaryotic type
IPR022953 Phosphofructokinase

PFAM

PF00365

PRINTS

PR00476

PIRSF

PIRSF000533

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q0IIG5

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

506544

UniGene

Bt.61411

RefSeq

NP_001068736

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC122655

GenPept

AAI22656