Version 5.4
Bos taurus Protein: TSPAN6
Summary
InnateDB Protein IDBP-684906.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPAN6
Protein Name Tetraspanin-6
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000056037
InnateDB Gene IDBG-633216 (TSPAN6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1901223 negative regulation of NIK/NF-kappaB signaling
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000301 Tetraspanin
IPR008952 Tetraspanin, EC2 domain
IPR018499 Tetraspanin/Peripherin
PFAM PF00335
PRINTS PR00259
PIRSF PIRSF002419
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q32KU6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 514741
UniGene
RefSeq NP_001033198
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109924
GenPept AAI09925

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca