InnateDB Protein
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IDBP-685204.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ALDH8A1
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Protein Name
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aldehyde dehydrogenase family 8 member A1
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000010485
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InnateDB Gene
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IDBG-633488 (ALDH8A1)
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Protein Structure
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Function |
Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, but shows considerable activity with NADP (in vitro) (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
Accession |
GO Term |
GO:0001758
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retinal dehydrogenase activity
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GO:0016491
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oxidoreductase activity
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GO:0016620
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oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR015590
Aldehyde dehydrogenase domain
IPR016161
Aldehyde/histidinol dehydrogenase
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PFAM |
PF00171
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q0P5F9
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
513537
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UniGene |
Bt.43302
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RefSeq |
NP_001069094
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC120092
BT029881
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GenPept |
AAI20093
ABM06132
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