Version 5.4
Bos taurus Protein: TXNIP
Summary
InnateDB Protein IDBP-685274.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TXNIP
Protein Name TXNIP proteinUncharacterized protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000026724
InnateDB Gene IDBG-633552 (TXNIP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004857 enzyme inhibitor activity
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006606 protein import into nucleus
GO:0006979 response to oxidative stress
GO:0030216 keratinocyte differentiation
GO:0043086 negative regulation of catalytic activity
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0051782 negative regulation of cell division
GO:0071228 cellular response to tumor cell
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR011021 Arrestin-like, N-terminal
IPR011022 Arrestin C-terminal-like domain
IPR014756 Immunoglobulin E-set
PFAM PF00339
PF02752
PRINTS
PIRSF
SMART SM01017
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A7Z054
UniProt Splice Variant
Entrez Gene 506790
UniGene Bt.12327
RefSeq NP_001095345
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC153252 DAAA02007321
GenPept AAI53253

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca