Version 5.4
Bos taurus Protein: FBXW8
Summary
InnateDB Protein IDBP-685370.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXW8
Protein Name F-box and WD repeat domain containing 8
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000056288
InnateDB Gene IDBG-633635 (FBXW8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
GO:0008283 cell proliferation
GO:0016567 protein ubiquitination
GO:0060712 spongiotrophoblast layer development
GO:0060716 labyrinthine layer blood vessel development
Cellular Component
GO:0005794 Golgi apparatus
GO:0019005 SCF ubiquitin ligase complex
GO:0031467 Cul7-RING ubiquitin ligase complex
GO:0048471 perinuclear region of cytoplasm
GO:1990393 3M complex
Protein Structure and Domains
PDB ID
InterPro IPR001810 F-box domain
IPR017986 WD40-repeat-containing domain
PFAM PF00646
PF12937
PF13013
PRINTS
PIRSF
SMART SM00256
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3N316
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:13597
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02045349 DAAA02045350 DAAA02045351 DAAA02045352
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca