InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.35140

Summary

InnateDB Protein

IDBP-685866.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.35140

Protein Name

tripeptidyl-peptidase 1 precursor

Synonyms

CLN2; TPP-1; TPP-I;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020469

InnateDB Gene

IDBG-634106 (BT.35140)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004175	endopeptidase activity
GO:0004252	serine-type endopeptidase activity
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0008236	serine-type peptidase activity
GO:0008240	tripeptidyl-peptidase activity
GO:0016787	hydrolase activity

Biological Process

GO:0006508	proteolysis
GO:0007040	lysosome organization
GO:0007399	nervous system development
GO:0030855	epithelial cell differentiation
GO:0043171	peptide catabolic process
GO:0045453	bone resorption
GO:0050885	neuromuscular process controlling balance

Cellular Component

GO:0005739	mitochondrion
GO:0005764	lysosome
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000209 Peptidase S8/S53 domain
IPR009020 Proteinase inhibitor, propeptide
IPR015366 Peptidase S53, propeptide

PFAM

PF00082
PF09286

PRINTS

PIRSF

SMART

SM00944

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1MK08

UniProt Splice Variant

Entrez Gene

515575

UniGene

Bt.35140

RefSeq

NP_001069186

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02040852 DAAA02040853

GenPept