InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: EPM2A

Summary

InnateDB Protein

IDBP-685909.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EPM2A

Protein Name

laforin

Synonyms

laforin;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020200

InnateDB Gene

IDBG-634153 (EPM2A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0004725	protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0008138	protein tyrosine/serine/threonine phosphatase activity
GO:0016787	hydrolase activity
GO:0016791	phosphatase activity
GO:0019203	carbohydrate phosphatase activity
GO:0030246	carbohydrate binding
GO:2001070	starch binding

Biological Process

GO:0006470	protein dephosphorylation
GO:0007399	nervous system development
GO:0016311	dephosphorylation
GO:0046855	inositol phosphate dephosphorylation
GO:0046959	habituation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005844	polysome

Protein Structure and Domains

PDB ID

InterPro

IPR000340 Dual specificity phosphatase, catalytic domain
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR002044 Carbohydrate binding module family 20
IPR013784 Carbohydrate-binding-like fold
IPR020422 Dual specificity phosphatase, subgroup, catalytic domain
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00782
PF00686

PRINTS

PIRSF

SMART

SM01065
SM00195

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite