InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: APOD

Summary

InnateDB Protein

IDBP-685931.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

APOD

Protein Name

apolipoprotein D precursor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000043789

InnateDB Gene

IDBG-634170 (APOD)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0008289	lipid binding
GO:0015485	cholesterol binding
GO:0036094	small molecule binding

Biological Process

GO:0000302	response to reactive oxygen species
GO:0006006	glucose metabolic process
GO:0006629	lipid metabolic process
GO:0006810	transport
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0042308	negative regulation of protein import into nucleus
GO:0048662	negative regulation of smooth muscle cell proliferation
GO:0051895	negative regulation of focal adhesion assembly
GO:0060588	negative regulation of lipoprotein lipid oxidation
GO:0071638	negative regulation of monocyte chemotactic protein-1 production
GO:1900016	negative regulation of cytokine production involved in inflammatory response
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion
GO:2000405	negative regulation of T cell migration

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005622	intracellular
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000566 Lipocalin/cytosolic fatty-acid binding domain
IPR002345 Lipocalin
IPR002446 Lipocalin, bacterial
IPR002969 Apolipoprotein D
IPR003057 Invertebrate colouration protein
IPR011038 Calycin-like
IPR022271 Lipocalin, ApoD type

PFAM

PF00061
PF08212

PRINTS

PR00179
PR01171
PR01219
PR01273

PIRSF

PIRSF036893

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt