InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CD8A

Summary

InnateDB Protein

IDBP-686708.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CD8A

Protein Name

T-cell surface glycoprotein CD8 alpha chain precursor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000028175

InnateDB Gene

IDBG-634911 (CD8A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0002456	T cell mediated immunity
GO:0007166	cell surface receptor signaling pathway
GO:0045065	cytotoxic T cell differentiation
GO:0050850	positive regulation of calcium-mediated signaling
GO:0051607	defense response to virus

Cellular Component

GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003596 Immunoglobulin V-set, subgroup
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF07686
PF00047

PRINTS

PIRSF

SMART

SM00406
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite