Version 5.4
Bos taurus Protein: TRIM27
Summary
InnateDB Protein IDBP-687052.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM27
Protein Name zinc finger protein RFP
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000001158
InnateDB Gene IDBG-635228 (TRIM27)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 82 interaction(s) predicted by orthology.
Predicted by orthology
Total 82 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0002820 negative regulation of adaptive immune response
GO:0006469 negative regulation of protein kinase activity
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032897 negative regulation of viral transcription
GO:0034314 Arp2/3 complex-mediated actin nucleation
GO:0042147 retrograde transport, endosome to Golgi
GO:0045087 innate immune response
GO:0045814 negative regulation of gene expression, epigenetic
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070206 protein trimerization
GO:0070534 protein K63-linked ubiquitination
GO:0072643 interferon-gamma secretion
GO:0090281 negative regulation of calcium ion import
GO:1900041 negative regulation of interleukin-2 secretion
GO:1902187 negative regulation of viral release from host cell
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0030904 retromer complex
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR000315 Zinc finger, B-box
IPR001841 Zinc finger, RING-type
IPR001870 B30.2/SPRY domain
IPR003877 SPRY domain
IPR003879 Butyrophylin-like
IPR006574 SPRY-associated
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR018957 Zinc finger, C3HC4 RING-type
IPR020457 Zinc finger, B-box, chordata
PFAM PF00643
PF13639
PF14634
PF00622
PF13765
PF00097
PRINTS PR01407
PR01406
PIRSF
SMART SM00336
SM00184
SM00449
SM00589
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q1LZA9
UniProt Splice Variant
Entrez Gene 520111
UniGene Bt.21774
RefSeq NP_001069267
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC116113 DAAA02055446
GenPept AAI16114

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca