InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.4977

Summary

InnateDB Protein

IDBP-687356.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.4977

Protein Name

cation-independent mannose-6-phosphate receptor

Synonyms

CI-MPR; CIMPR;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000037502

InnateDB Gene

IDBG-635488 (BT.4977)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001948	glycoprotein binding
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0005520	insulin-like growth factor binding
GO:0005537	mannose binding
GO:0042802	identical protein binding
GO:0051219	phosphoprotein binding

Biological Process

GO:0006810

transport

Cellular Component

GO:0005634	nucleus
GO:0005641	nuclear envelope lumen
GO:0005737	cytoplasm
GO:0005768	endosome
GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030139	endocytic vesicle
GO:0030140	trans-Golgi network transport vesicle
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000479 Cation-independent mannose-6-phosphate receptor
IPR000562 Fibronectin, type II, collagen-binding
IPR009011 Mannose-6-phosphate receptor binding domain
IPR013806 Kringle-like fold
IPR018939 Autophagy-related protein 27

PFAM

PF00878
PF00040
PF09451

PRINTS

PIRSF

SMART

SM00059

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite