Version 5.4
| Bos taurus Protein: PPP3R1 | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-687517.2 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | PPP3R1 | ||||||||||
| Protein Name | Calcineurin subunit B type 1 | ||||||||||
| Synonyms | |||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Protein | ENSBTAP00000014038 | ||||||||||
| InnateDB Gene | IDBG-635671 (PPP3R1) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. | ||||||||||
| Subcellular Localization | Cytoplasm, cytosol {ECO:0000250}. Cell membrane {ECO:0000250}. Cell membrane, sarcolemma. Note=Translocates from the cytosol to the sarcolemma in a CIB1- dependent manner during cardiomyocytes hypertrophy. {ECO:0000250}. | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | |||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | |||||||||||
| InterPro |
IPR002048
EF-hand domain |
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| PFAM |
PF00036
PF13202 PF13405 |
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| PRINTS | |||||||||||
| PIRSF | |||||||||||
| SMART |
SM00054
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| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | P63099 | ||||||||||
| PhosphoSite | PhosphoSite- | ||||||||||
| TrEMBL | A9ZTJ9 | ||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 282321 | ||||||||||
| UniGene | |||||||||||
| RefSeq | NP_777008 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | AB375794 X71666 | ||||||||||
| GenPept | BAF99032 CAA50659 | ||||||||||