InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: OGT

Summary

InnateDB Protein

IDBP-687646.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

OGT

Protein Name

UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000042834

InnateDB Gene

IDBG-635754 (OGT)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.

Predicted by orthology
Total	42 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
GO:0008047	enzyme activator activity
GO:0016262	protein N-acetylglucosaminyltransferase activity
GO:0043995	histone acetyltransferase activity (H4-K5 specific)
GO:0043996	histone acetyltransferase activity (H4-K8 specific)
GO:0046972	histone acetyltransferase activity (H4-K16 specific)
GO:0097363	protein O-GlcNAc transferase activity

Biological Process

GO:0006110	regulation of glycolytic process
GO:0006493	protein O-linked glycosylation
GO:0006915	apoptotic process
GO:0030854	positive regulation of granulocyte differentiation
GO:0031397	negative regulation of protein ubiquitination
GO:0032868	response to insulin
GO:0032922	circadian regulation of gene expression
GO:0035020	regulation of Rac protein signal transduction
GO:0043085	positive regulation of catalytic activity
GO:0043981	histone H4-K5 acetylation
GO:0043982	histone H4-K8 acetylation
GO:0043984	histone H4-K16 acetylation
GO:0045862	positive regulation of proteolysis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046626	regulation of insulin receptor signaling pathway
GO:0048015	phosphatidylinositol-mediated signaling
GO:0051571	positive regulation of histone H3-K4 methylation
GO:0061087	positive regulation of histone H3-K27 methylation
GO:0071300	cellular response to retinoic acid
GO:0080182	histone H3-K4 trimethylation
GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis

Cellular Component

GO:0000123	histone acetyltransferase complex
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005815	microtubule organizing center
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0070688	MLL5-L complex

Protein Structure and Domains

PDB ID

InterPro

IPR001440 Tetratricopeptide TPR1
IPR013026 Tetratricopeptide repeat-containing domain
IPR013105 Tetratricopeptide TPR2
IPR019734 Tetratricopeptide repeat

PFAM

PF00515
PF07719
PF13174
PF13176
PF13181

PRINTS

PIRSF

SMART

SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite