InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MYO7A

Summary

InnateDB Protein

IDBP-687878.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYO7A

Protein Name

myosin VIIA

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000005191

InnateDB Gene

IDBG-635882 (MYO7A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000146	microfilament motor activity
GO:0003774	motor activity
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0005524	ATP binding
GO:0019904	protein domain specific binding
GO:0030507	spectrin binding
GO:0051015	actin filament binding

Biological Process

GO:0001845	phagolysosome assembly
GO:0006886	intracellular protein transport
GO:0006909	phagocytosis
GO:0007040	lysosome organization
GO:0007600	sensory perception
GO:0007601	visual perception
GO:0007605	sensory perception of sound
GO:0008152	metabolic process
GO:0030030	cell projection organization
GO:0030048	actin filament-based movement
GO:0042472	inner ear morphogenesis
GO:0042490	mechanoreceptor differentiation
GO:0042491	auditory receptor cell differentiation
GO:0048563	post-embryonic organ morphogenesis
GO:0048839	inner ear development
GO:0050953	sensory perception of light stimulus
GO:0050957	equilibrioception
GO:0051875	pigment granule localization
GO:0051904	pigment granule transport
GO:0060088	auditory receptor cell stereocilium organization
GO:0060113	inner ear receptor cell differentiation

Cellular Component

GO:0001750	photoreceptor outer segment
GO:0001917	photoreceptor inner segment
GO:0005737	cytoplasm
GO:0005765	lysosomal membrane
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0016324	apical plasma membrane
GO:0016459	myosin complex
GO:0032391	photoreceptor connecting cilium
GO:0032420	stereocilium
GO:0042470	melanosome
GO:0045202	synapse

Protein Structure and Domains

PDB ID

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR000299 FERM domain
IPR000857 MyTH4 domain
IPR001452 SH3 domain
IPR001609 Myosin head, motor domain
IPR018979 FERM, N-terminal
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR029071 Ubiquitin-related domain

PFAM