Bos taurus Gene: MYO7A
Summary
InnateDB Gene IDBG-635882.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYO7A
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003955
Encoded Proteins
myosin VIIA
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137474:
This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:57332143-57419714
Strand Forward strand
Band
Transcripts
ENSBTAT00000005191 ENSBTAP00000005191
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000146 microfilament motor activity
GO:0003774 motor activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0019904 protein domain specific binding
GO:0030507 spectrin binding
GO:0051015 actin filament binding
Biological Process
GO:0001845 phagolysosome assembly
GO:0006886 intracellular protein transport
GO:0006909 phagocytosis
GO:0007040 lysosome organization
GO:0007600 sensory perception
GO:0007601 visual perception
GO:0007605 sensory perception of sound
GO:0008152 metabolic process
GO:0030030 cell projection organization
GO:0030048 actin filament-based movement
GO:0042472 inner ear morphogenesis
GO:0042490 mechanoreceptor differentiation
GO:0042491 auditory receptor cell differentiation
GO:0048563 post-embryonic organ morphogenesis
GO:0048839 inner ear development
GO:0050953 sensory perception of light stimulus
GO:0050957 equilibrioception
GO:0051875 pigment granule localization
GO:0051904 pigment granule transport
GO:0060088 auditory receptor cell stereocilium organization
GO:0060113 inner ear receptor cell differentiation
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0016324 apical plasma membrane
GO:0016459 myosin complex
GO:0032391 photoreceptor connecting cilium
GO:0032420 stereocilium
GO:0042470 melanosome
GO:0045202 synapse
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
The canonical retinoid cycle in rods (twilight vision) pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Visual phototransduction pathway
Disease pathway
Disease pathway
The canonical retinoid cycle in rods (twilight vision) pathway
Visual phototransduction pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL F1MHG0
UniProt Splice Variant
Entrez Gene 535092
UniGene Bt.110077 Bt.44957
RefSeq XM_865073
HUGO HGNC:7606
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02041112 DAAA02041113
GenPept
RNA Seq Atlas 535092
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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