InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: AR

Summary

InnateDB Protein

IDBP-688339.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Protein Name

androgen receptor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000030053

InnateDB Gene

IDBG-636404 (AR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 262 interaction(s) predicted by orthology.

Predicted by orthology
Total	262 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003707	steroid hormone receptor activity
GO:0004882	androgen receptor activity
GO:0005496	steroid binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0019899	enzyme binding
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding
GO:0070974	POU domain binding

Biological Process

GO:0001701	in utero embryonic development
GO:0003073	regulation of systemic arterial blood pressure
GO:0003382	epithelial cell morphogenesis
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0007283	spermatogenesis
GO:0007338	single fertilization
GO:0008584	male gonad development
GO:0009566	fertilization
GO:0009987	cellular process
GO:0010468	regulation of gene expression
GO:0019102	male somatic sex determination
GO:0030521	androgen receptor signaling pathway
GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
GO:0033327	Leydig cell differentiation
GO:0035264	multicellular organism growth
GO:0043401	steroid hormone mediated signaling pathway
GO:0043410	positive regulation of MAPK cascade
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway
GO:0048608	reproductive structure development
GO:0048638	regulation of developmental growth
GO:0048645	organ formation
GO:0048808	male genitalia morphogenesis
GO:0050680	negative regulation of epithelial cell proliferation
GO:0050790	regulation of catalytic activity
GO:0060520	activation of prostate induction by androgen receptor signaling pathway
GO:0060571	morphogenesis of an epithelial fold
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis
GO:0060685	regulation of prostatic bud formation
GO:0060736	prostate gland growth
GO:0060740	prostate gland epithelium morphogenesis
GO:0060742	epithelial cell differentiation involved in prostate gland development
GO:0060748	tertiary branching involved in mammary gland duct morphogenesis
GO:0060749	mammary gland alveolus development
GO:0061458	reproductive system development
GO:0072520	seminiferous tubule development

Cellular Component

GO:0005634	nucleus
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001103 Androgen receptor
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR008946 Nuclear hormone receptor, ligand-binding

PFAM

PF00104
PF02166
PF00105

PRINTS

PR00521
PR00047

PIRSF

SMART

SM00430
SM00399

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt