Version 5.4
Bos taurus Protein: RAG2
Summary
InnateDB Protein IDBP-688722.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAG2
Protein Name V(D)J recombination-activating protein 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000039446
InnateDB Gene IDBG-636766 (RAG2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0008270 zinc ion binding
GO:0035064 methylated histone binding
GO:0035091 phosphatidylinositol binding
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding
Biological Process
GO:0002326 B cell lineage commitment
GO:0002331 pre-B cell allelic exclusion
GO:0002358 B cell homeostatic proliferation
GO:0002360 T cell lineage commitment
GO:0006310 DNA recombination
GO:0030183 B cell differentiation
GO:0030217 T cell differentiation
GO:0033077 T cell differentiation in thymus
GO:0033151 V(D)J recombination
GO:0046622 positive regulation of organ growth
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR004321 V-D-J recombination activating protein 2
IPR011011 Zinc finger, FYVE/PHD-type
IPR011043 Galactose oxidase/kelch, beta-propeller
PFAM PF03089
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8SQE1
UniProt Splice Variant
Entrez Gene 782387
UniGene Bt.88102
RefSeq NP_001075938
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF447537 BC133486 DAAA02041331
GenPept AAI33487 AAL78952

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca