InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.48865

Summary

InnateDB Protein

IDBP-688865.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.48865

Protein Name

bile acid receptor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000018079

InnateDB Gene

IDBG-636894 (BT.48865)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001190	RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003707	steroid hormone receptor activity
GO:0004879	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004887	thyroid hormone receptor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0032052	bile acid binding
GO:0038181	bile acid receptor activity
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding
GO:0046965	retinoid X receptor binding
GO:1902122	chenodeoxycholic acid binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0008206	bile acid metabolic process
GO:0030522	intracellular receptor signaling pathway
GO:0034255	regulation of urea metabolic process
GO:0038185	intracellular bile acid receptor signaling pathway
GO:0043401	steroid hormone mediated signaling pathway
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0070858	negative regulation of bile acid biosynthetic process
GO:0071229	cellular response to acid
GO:0071417	cellular response to organonitrogen compound
GO:2000213	positive regulation of glutamate metabolic process
GO:2001250	positive regulation of ammonia assimilation cycle

Cellular Component

GO:0005634	nucleus
GO:0005719	nuclear euchromatin

Protein Structure and Domains

PDB ID

InterPro

IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR001723 Steroid hormone receptor
IPR001728 Thyroid hormone receptor
IPR008946 Nuclear hormone receptor, ligand-binding

PFAM

PF00104
PF00105

PRINTS

PR00047
PR00398
PR00546

PIRSF

SMART

SM00430
SM00399

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt