InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: IRF4

Summary

InnateDB Protein

IDBP-688969.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IRF4

Protein Name

interferon regulatory factor 4

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000003812

InnateDB Gene

IDBG-636960 (IRF4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 82 interaction(s) predicted by orthology.

Predicted by orthology
Total	82 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000975	regulatory region DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0016279	protein-lysine N-methyltransferase activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006479	protein methylation
GO:0018022	peptidyl-lysine methylation
GO:0034122	negative regulation of toll-like receptor signaling pathway
GO:0042832	defense response to protozoan
GO:0043011	myeloid dendritic cell differentiation
GO:0043388	positive regulation of DNA binding
GO:0043966	histone H3 acetylation
GO:0043967	histone H4 acetylation
GO:0045082	positive regulation of interleukin-10 biosynthetic process
GO:0045086	positive regulation of interleukin-2 biosynthetic process
GO:0045368	positive regulation of interleukin-13 biosynthetic process
GO:0045404	positive regulation of interleukin-4 biosynthetic process
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0072540	T-helper 17 cell lineage commitment