InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PKN2

Summary

InnateDB Protein

IDBP-689122.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PKN2

Protein Name

protein kinase N2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000029201

InnateDB Gene

IDBG-637137 (PKN2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0042826	histone deacetylase binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006468	protein phosphorylation
GO:0007165	signal transduction
GO:0010631	epithelial cell migration
GO:0016310	phosphorylation
GO:0032467	positive regulation of cytokinesis
GO:0043297	apical junction assembly
GO:0045931	positive regulation of mitotic cell cycle
GO:2000145	regulation of cell motility

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0030027	lamellipodium
GO:0030496	midbody
GO:0032154	cleavage furrow
GO:0043296	apical junction complex
GO:0045111	intermediate filament cytoskeleton

Protein Structure and Domains

PDB ID

InterPro

IPR000008 C2 domain
IPR000719 Protein kinase domain
IPR000961 AGC-kinase, C-terminal
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR011072 HR1 rho-binding repeat
IPR017892 Protein kinase, C-terminal
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00168
PF00069
PF07714
PF02185
PF00433

PRINTS

PR00360
PR00109

PIRSF

SMART

SM00239
SM00133
SM00220
SM00742
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt