Version 5.4
Bos taurus Gene: PKN2
Summary
InnateDB Gene IDBG-637137.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PKN2
Gene Name serine/threonine-protein kinase N2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021900
Encoded Proteins
IDBP-689122
protein kinase N2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000065243:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:55231810-55365736
Strand Reverse strand
Band
Transcripts
ENSBTAT00000029201 ENSBTAP00000029201
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0042826 histone deacetylase binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0010631 epithelial cell migration
GO:0016310 phosphorylation
GO:0032467 positive regulation of cytokinesis
GO:0043297 apical junction assembly
GO:0045931 positive regulation of mitotic cell cycle
GO:2000145 regulation of cell motility
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0030027 lamellipodium
GO:0030496 midbody
GO:0032154 cleavage furrow
GO:0043296 apical junction complex
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000065243
View Gene Order
ENSMUSG00000004591
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
rhoa_pathway
RhoA signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.106097
RefSeq NM_001193242
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca