Bos taurus Protein: CREM | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-689213.3 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | CREM | ||||||||||
Protein Name | cAMP-responsive element modulator | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Protein | ENSBTAP00000050114 | ||||||||||
InnateDB Gene | IDBG-637209 (CREM) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform 1 and isoform 2 are transcriptional activators. Plays a role in spermatogenesis and is involved in spermatid maturation (By similarity). {ECO:0000250}. | ||||||||||
Subcellular Localization | Nucleus {ECO:0000255PROSITE- ProRule:PRU00312, ECO:0000255PROSITE-ProRule:PRU00978}. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | |||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | |||||||||||
InterPro |
IPR001630
cAMP response element binding (CREB) protein IPR003102 Coactivator CBP, pKID IPR004827 Basic-leucine zipper domain |
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PFAM |
PF02173
PF00170 PF07716 |
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PRINTS |
PR00041
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PIRSF | |||||||||||
SMART |
SM00338
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TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | Q1LZH5 | ||||||||||
PhosphoSite | PhosphoSite- | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 540605 | ||||||||||
UniGene | Bt.48141 | ||||||||||
RefSeq | XP_005214310 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | BC102677 BC115995 | ||||||||||
GenPept | AAI02678 AAI15996 | ||||||||||