InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PHF8

Summary

InnateDB Protein

IDBP-689506.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PHF8

Protein Name

PHD finger protein 8

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017673

InnateDB Gene

IDBG-637450 (PHF8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0005506	iron ion binding
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032452	histone demethylase activity
GO:0032454	histone demethylase activity (H3-K9 specific)
GO:0035064	methylated histone binding
GO:0035575	histone demethylase activity (H4-K20 specific)
GO:0051864	histone demethylase activity (H3-K36 specific)
GO:0071558	histone demethylase activity (H3-K27 specific)

Biological Process

GO:0000082	G1/S transition of mitotic cell cycle
GO:0033169	histone H3-K9 demethylation
GO:0035574	histone H4-K20 demethylation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045943	positive regulation of transcription from RNA polymerase I promoter
GO:0061188	negative regulation of chromatin silencing at rDNA
GO:0070544	histone H3-K36 demethylation
GO:0071557	histone H3-K27 demethylation