Version 5.4
Bos taurus Protein: CRY1
Summary
InnateDB Protein IDBP-689765.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CRY1
Protein Name cryptochrome-1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000051134
InnateDB Gene IDBG-637730 (CRY1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.
Predicted by orthology
Total 38 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000989 transcription factor binding transcription factor activity
GO:0001047 core promoter binding
GO:0003690 double-stranded DNA binding
GO:0003913 DNA photolyase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0035257 nuclear hormone receptor binding
GO:0042826 histone deacetylase binding
GO:0043130 ubiquitin binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006094 gluconeogenesis
GO:0006281 DNA repair
GO:0006975 DNA damage induced protein phosphorylation
GO:0007623 circadian rhythm
GO:0019915 lipid storage
GO:0031397 negative regulation of protein ubiquitination
GO:0032868 response to insulin
GO:0032922 circadian regulation of gene expression
GO:0033762 response to glucagon
GO:0042593 glucose homeostasis
GO:0042752 regulation of circadian rhythm
GO:0042754 negative regulation of circadian rhythm
GO:0043153 entrainment of circadian clock by photoperiod
GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:2000001 regulation of DNA damage checkpoint
GO:2000323 negative regulation of glucocorticoid receptor signaling pathway
GO:2000850 negative regulation of glucocorticoid secretion
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR005101 DNA photolyase, FAD-binding/Cryptochrome, C-terminal
IPR006050 DNA photolyase, N-terminal
PFAM PF03441
PF00875
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MXB2
UniProt Splice Variant
Entrez Gene 535947
UniGene
RefSeq NP_001098885
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02013749 DAAA02013750 DAAA02013751 DAAA02013752
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca