InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CTH

Summary

InnateDB Protein

IDBP-689979.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CTH

Protein Name

cystathionine gamma-lyase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000056275

InnateDB Gene

IDBG-637937 (CTH)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004123	cystathionine gamma-lyase activity
GO:0005515	protein binding
GO:0030170	pyridoxal phosphate binding
GO:0044540	L-cystine L-cysteine-lyase (deaminating)

Biological Process

GO:0008152	metabolic process
GO:0009058	biosynthetic process
GO:0018272	protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine
GO:0043066	negative regulation of apoptotic process
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044524	protein sulfhydration
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0051289	protein homotetramerization
GO:0070814	hydrogen sulfide biosynthetic process
GO:2001234	negative regulation of apoptotic signaling pathway

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000192 Aminotransferase class V domain
IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme
IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase
IPR004839 Aminotransferase, class I/classII
IPR015424 Pyridoxal phosphate-dependent transferase

PFAM

PF00266
PF01053
PF01041
PF00155

PRINTS

PIRSF

PIRSF001434
PIRSF000390

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite