Bos taurus Gene: CTH | |||||||||||||||||||||
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Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-637937.3 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | CTH | ||||||||||||||||||||
Gene Name | cystathionine gamma-lyase | ||||||||||||||||||||
Synonyms | |||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||
Ensembl Gene | ENSBTAG00000014791 | ||||||||||||||||||||
Encoded Proteins |
cystathionine gamma-lyase
cystathionine gamma-lyase
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Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116761:
This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010] |
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Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 3:75082359-75109443 | ||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||
Band | |||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||
NETPATH | |||||||||||||||||||||
REACTOME |
Degradation of cysteine and homocysteine pathway
Cysteine formation from homocysteine pathway
Sulfur amino acid metabolism pathway
Metabolism of amino acids and derivatives pathway
Metabolism pathway
Degradation of cysteine and homocysteine pathway
Cysteine formation from homocysteine pathway
Metabolism pathway
Metabolism of amino acids and derivatives pathway
Sulfur amino acid metabolism pathway
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KEGG |
Glycine, serine and threonine metabolism pathway
Selenocompound metabolism pathway
Cysteine and methionine metabolism pathway
Glycine, serine and threonine metabolism pathway
Selenocompound metabolism pathway
Cysteine and methionine metabolism pathway
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INOH |
Methionine Cysteine metabolism pathway
Glycine Serine metabolism pathway
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PID NCI | |||||||||||||||||||||
Cross-References | |||||||||||||||||||||
SwissProt | |||||||||||||||||||||
TrEMBL | B0JYP8 | ||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | 786781 | ||||||||||||||||||||
UniGene | Bt.37399 Bt.73096 Bt.89329 | ||||||||||||||||||||
RefSeq | XM_005204481 XM_005204482 NM_001024567 XM_001254364 | ||||||||||||||||||||
HUGO | |||||||||||||||||||||
OMIM | |||||||||||||||||||||
CCDS | |||||||||||||||||||||
HPRD | |||||||||||||||||||||
IMGT | |||||||||||||||||||||
EMBL | BC151523 DAAA02008397 | ||||||||||||||||||||
GenPept | AAI51524 | ||||||||||||||||||||
RNA Seq Atlas | 539159 786781 | ||||||||||||||||||||