Version 5.4
Bos taurus Protein: NCF4
Summary
InnateDB Protein IDBP-690150.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NCF4
Protein Name neutrophil cytosol factor 4
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000009911
InnateDB Gene IDBG-638107 (NCF4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016176 superoxide-generating NADPH oxidase activator activity
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0043020 NADPH oxidase complex
Protein Structure and Domains
PDB ID
InterPro IPR000270 Phox/Bem1p
IPR000919 Neutrophil cytosol factor P40
IPR001452 SH3 domain
IPR001683 Phox homologous domain
IPR011511 Variant SH3 domain
PFAM PF00564
PF00018
PF14604
PF00787
PF07653
PRINTS PR00497
PR00452
PIRSF
SMART SM00666
SM00326
SM00312
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q2HJA6
UniProt Splice Variant
Entrez Gene 507859
UniGene Bt.7625
RefSeq NP_001039448
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC113230 DAAA02013838
GenPept AAI13231

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca