InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ITGA8

Summary

InnateDB Protein

IDBP-690272.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ITGA8

Protein Name

integrin, alpha 8

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000039219

InnateDB Gene

IDBG-638143 (ITGA8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0001656	metanephros development
GO:0007155	cell adhesion
GO:0007229	integrin-mediated signaling pathway
GO:0007613	memory
GO:0030030	cell projection organization
GO:0030198	extracellular matrix organization
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway
GO:0042472	inner ear morphogenesis
GO:0045184	establishment of protein localization
GO:0048745	smooth muscle tissue development
GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation

Cellular Component

GO:0008305	integrin complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0045177	apical part of cell

Protein Structure and Domains

PDB ID

InterPro

IPR000413 Integrin alpha chain
IPR013517 FG-GAP repeat
IPR013519 Integrin alpha beta-propellor
IPR013649 Integrin alpha-2
IPR018184 Integrin alpha chain, C-terminal cytoplasmic region, conserved site

PFAM

PF01839
PF14312
PF08441
PF00357

PRINTS

PR01185

PIRSF

SMART

SM00191

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt