Version 5.4
Bos taurus Protein: TRAF5
Summary
InnateDB Protein IDBP-690290.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRAF5
Protein Name TNF receptor-associated factor 5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000015940
InnateDB Gene IDBG-638230 (TRAF5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.
Predicted by orthology
Total 50 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0031625 ubiquitin protein ligase binding
GO:0031996 thioesterase binding
GO:0046872 metal ion binding
Biological Process
GO:0007165 signal transduction
GO:0008284 positive regulation of cell proliferation
GO:0016567 protein ubiquitination
GO:0042981 regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR001293 Zinc finger, TRAF-type
IPR001841 Zinc finger, RING-type
IPR002083 MATH
IPR008974 TRAF-like
IPR012227 TNF receptor-associated factor TRAF
PFAM PF13639
PF14634
PF00917
PRINTS
PIRSF PIRSF015614
SMART SM00184
SM00061
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A7YWC7
UniProt Splice Variant
Entrez Gene 507234
UniGene Bt.8981
RefSeq NP_001098810
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134494 DAAA02043784 DAAA02043785
GenPept AAI34495

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca