InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: HOGA1

Summary

InnateDB Protein

IDBP-690502.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HOGA1

Protein Name

Probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial

Synonyms

C10orf65; DHDPSL; NPL2;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000016909

InnateDB Gene

IDBG-638436 (HOGA1)

Protein Structure

UniProt Annotation

Function

Catalyzes the final step in the metabolic pathway of hydroxyproline. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000269PubMed:21998747}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0008700	4-hydroxy-2-oxoglutarate aldolase activity
GO:0016829	lyase activity
GO:0042803	protein homodimerization activity

Biological Process

GO:0008152	metabolic process
GO:0009436	glyoxylate catabolic process
GO:0019470	4-hydroxyproline catabolic process
GO:0033609	oxalate metabolic process
GO:0042866	pyruvate biosynthetic process
GO:0046487	glyoxylate metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002220 DapA-like

PFAM

PF00701

PRINTS

PR00146

PIRSF

PIRSF001365

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q0P5I5

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

506001

UniGene

Bt.54337

RefSeq

NP_001068705

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC119998 BT026547

GenPept

AAI19999 ABH06334