Version 5.4
Bos taurus Protein: CD34
Summary
InnateDB Protein IDBP-690525.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD34
Protein Name hematopoietic progenitor cell antigen CD34
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000013963
InnateDB Gene IDBG-638449 (CD34)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008134 transcription factor binding
GO:0030246 carbohydrate binding
GO:0043199 sulfate binding
Biological Process
GO:0001894 tissue homeostasis
GO:0001935 endothelial cell proliferation
GO:0003094 glomerular filtration
GO:0003158 endothelium development
GO:0006536 glutamate metabolic process
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0008217 regulation of blood pressure
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016337 single organismal cell-cell adhesion
GO:0030097 hemopoiesis
GO:0030195 negative regulation of blood coagulation
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032733 positive regulation of interleukin-10 production
GO:0038001 paracrine signaling
GO:0042482 positive regulation of odontogenesis
GO:0045019 negative regulation of nitric oxide biosynthetic process
GO:0045766 positive regulation of angiogenesis
GO:0048870 cell motility
GO:0050900 leukocyte migration
GO:0060290 transdifferentiation
GO:0061042 vascular wound healing
GO:0071425 hematopoietic stem cell proliferation
GO:0071636 positive regulation of transforming growth factor beta production
GO:0071657 positive regulation of granulocyte colony-stimulating factor production
GO:0071971 extracellular vesicular exosome assembly
GO:0072011 glomerular endothelium development
GO:0072089 stem cell proliferation
GO:0072254 metanephric glomerular mesangial cell differentiation
GO:1900035 negative regulation of cellular response to heat
GO:1900038 negative regulation of cellular response to hypoxia
GO:1900041 negative regulation of interleukin-2 secretion
GO:1900168 positive regulation of glial cell line-derived neurotrophic factor secretion
GO:1901215 negative regulation of neuron death
GO:2001214 positive regulation of vasculogenesis
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0045171 intercellular bridge
GO:0048471 perinuclear region of cytoplasm
GO:0071944 cell periphery
Protein Structure and Domains
PDB ID
InterPro IPR008083 CD34 antigen
IPR013836 CD34/Podocalyxin
PFAM PF06365
PRINTS PR01700
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MN25
UniProt Splice Variant
Entrez Gene 281051
UniGene Bt.4571
RefSeq NP_776434
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02043873
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca