Bos taurus Gene: CD34
InnateDB Gene IDBG-638449.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD34
Gene Name hematopoietic progenitor cell antigen CD34 precursor
Species Bos taurus
Ensembl Gene ENSBTAG00000010562
Encoded Proteins
hematopoietic progenitor cell antigen CD34
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174059:
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:77367502-77389361
Strand Forward strand
ENSBTAT00000013963 ENSBTAP00000013963
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008134 transcription factor binding
GO:0030246 carbohydrate binding
GO:0043199 sulfate binding
Biological Process
GO:0001894 tissue homeostasis
GO:0001935 endothelial cell proliferation
GO:0003094 glomerular filtration
GO:0003158 endothelium development
GO:0006536 glutamate metabolic process
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0008217 regulation of blood pressure
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016337 single organismal cell-cell adhesion
GO:0030097 hemopoiesis
GO:0030195 negative regulation of blood coagulation
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032733 positive regulation of interleukin-10 production
GO:0038001 paracrine signaling
GO:0042482 positive regulation of odontogenesis
GO:0045019 negative regulation of nitric oxide biosynthetic process
GO:0045766 positive regulation of angiogenesis
GO:0048870 cell motility
GO:0050900 leukocyte migration
GO:0060290 transdifferentiation
GO:0061042 vascular wound healing
GO:0071425 hematopoietic stem cell proliferation
GO:0071636 positive regulation of transforming growth factor beta production
GO:0071657 positive regulation of granulocyte colony-stimulating factor production
GO:0071971 extracellular vesicular exosome assembly
GO:0072011 glomerular endothelium development
GO:0072089 stem cell proliferation
GO:0072254 metanephric glomerular mesangial cell differentiation
GO:1900035 negative regulation of cellular response to heat
GO:1900038 negative regulation of cellular response to hypoxia
GO:1900041 negative regulation of interleukin-2 secretion
GO:1900168 positive regulation of glial cell line-derived neurotrophic factor secretion
GO:1901215 negative regulation of neuron death
GO:2001214 positive regulation of vasculogenesis
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0045171 intercellular bridge
GO:0048471 perinuclear region of cytoplasm
GO:0071944 cell periphery
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Immune System pathway
Adaptive Immune System pathway
Hematopoietic cell lineage pathway
Cell adhesion molecules (CAMs) pathway
Cell adhesion molecules (CAMs) pathway
Hematopoietic cell lineage pathway
C-MYB transcription factor network
UniProt Splice Variant
Entrez Gene
UniGene Bt.4571
RefSeq NM_174009
RNA Seq Atlas