InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ASPM

Summary

InnateDB Protein

IDBP-690675.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ASPM

Protein Name

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000010340

InnateDB Gene

IDBG-638531 (ASPM)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding

Biological Process

GO:0001764	neuron migration
GO:0002052	positive regulation of neuroblast proliferation
GO:0007283	spermatogenesis
GO:0007420	brain development
GO:0021873	forebrain neuroblast division
GO:0045665	negative regulation of neuron differentiation
GO:0045769	negative regulation of asymmetric cell division
GO:0048477	oogenesis
GO:0048589	developmental growth
GO:0051661	maintenance of centrosome location
GO:0090263	positive regulation of canonical Wnt signaling pathway

Cellular Component

GO:0000922	spindle pole
GO:0030496	midbody

Protein Structure and Domains

PDB ID

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR001715 Calponin homology domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR016024 Armadillo-type fold
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00612
PF00307
PF11971

PRINTS

PIRSF

SMART

SM00015
SM00033

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite