InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: HERC2

Summary

InnateDB Protein

IDBP-690905.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HERC2

Protein Name

hect domain and RLD 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000018496

InnateDB Gene

IDBG-638724 (HERC2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.

Predicted by orthology
Total	38 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity
GO:0020037	heme binding
GO:0031625	ubiquitin protein ligase binding
GO:0032183	SUMO binding
GO:0046872	metal ion binding

Biological Process

GO:0006281	DNA repair
GO:0006974	cellular response to DNA damage stimulus
GO:0007283	spermatogenesis
GO:0016567	protein ubiquitination

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000408 Regulator of chromosome condensation, RCC1
IPR000433 Zinc finger, ZZ-type
IPR000569 HECT
IPR000859 CUB domain
IPR001199 Cytochrome b5-like heme/steroid binding domain
IPR004939 Anaphase-promoting complex, subunit 10/DOC domain
IPR006624 Beta-propeller repeat TECPR
IPR008979 Galactose-binding domain-like
IPR009060 UBA-like
IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
IPR010606 Mib-herc2
IPR016181 Acyl-CoA N-acyltransferase
IPR021097 CPH domain

PFAM