InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ARHGAP6

Summary

InnateDB Protein

IDBP-691151.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ARHGAP6

Protein Name

Rho GTPase activating protein 6

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000003400

InnateDB Gene

IDBG-639034 (ARHGAP6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005100	Rho GTPase activator activity
GO:0016004	phospholipase activator activity
GO:0043274	phospholipase binding

Biological Process

GO:0007015	actin filament organization
GO:0007165	signal transduction
GO:0007202	activation of phospholipase C activity
GO:0010518	positive regulation of phospholipase activity
GO:0032321	positive regulation of Rho GTPase activity
GO:0043087	regulation of GTPase activity
GO:0043547	positive regulation of GTPase activity
GO:0048041	focal adhesion assembly
GO:0051497	negative regulation of stress fiber assembly
GO:0051895	negative regulation of focal adhesion assembly

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0015629	actin cytoskeleton

Protein Structure and Domains

PDB ID

InterPro

IPR000198 Rho GTPase-activating protein domain
IPR008936 Rho GTPase activation protein

PFAM

PF00620

PRINTS

PIRSF

SMART

SM00324

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1N6V1

UniProt Splice Variant

Entrez Gene

100140016

UniGene

RefSeq

NP_001178283

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02075018

GenPept