InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: EPS8

Summary

InnateDB Protein

IDBP-691360.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EPS8

Protein Name

epidermal growth factor receptor kinase substrate 8

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000000479

InnateDB Gene

IDBG-639166 (EPS8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 48 interaction(s) predicted by orthology.

Predicted by orthology
Total	48 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding
GO:0048365	Rac GTPase binding

Biological Process

GO:0008344	adult locomotory behavior
GO:0008360	regulation of cell shape
GO:0010458	exit from mitosis
GO:0016601	Rac protein signal transduction
GO:0030832	regulation of actin filament length
GO:0031532	actin cytoskeleton reorganization
GO:0036336	dendritic cell migration
GO:0048149	behavioral response to ethanol
GO:0051016	barbed-end actin filament capping
GO:0051017	actin filament bundle assembly
GO:0051764	actin crosslink formation
GO:0070358	actin polymerization-dependent cell motility

Cellular Component

GO:0005938	cell cortex
GO:0014069	postsynaptic density
GO:0017146	N-methyl-D-aspartate selective glutamate receptor complex
GO:0032420	stereocilium
GO:0032587	ruffle membrane
GO:0045202	synapse
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001452 SH3 domain
IPR006020 PTB/PI domain
IPR011511 Variant SH3 domain
IPR013625 Tensin phosphotyrosine-binding domain
IPR013761 Sterile alpha motif/pointed domain

PFAM

PF00018
PF14604
PF00640
PF14719
PF07653
PF08416

PRINTS

PR00452

PIRSF

SMART

SM00326
SM00462

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt