InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ECHS1

Summary

InnateDB Protein

IDBP-691707.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ECHS1

Protein Name

Enoyl-CoA hydratase, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000042386

InnateDB Gene

IDBG-639539 (ECHS1)

Protein Structure

UniProt Annotation

Function

Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. {ECO:0000250}.

Subcellular Localization

Mitochondrion matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004300	enoyl-CoA hydratase activity
GO:0005515	protein binding
GO:0016829	lyase activity

Biological Process

GO:0006629	lipid metabolic process
GO:0006631	fatty acid metabolic process
GO:0006635	fatty acid beta-oxidation
GO:0008152	metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001753 Crotonase superfamily
IPR029045 ClpP/crotonase-like domain

PFAM

PF00378

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q58DM8

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

281748

UniGene

Bt.64629

RefSeq

NP_001020377

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC109605 BT021569 DQ058603 DQ058610

GenPept

AAI09606 AAX46416 AAY83878 AAY83884