Version 5.4
Bos taurus Protein: IDI1
Summary
InnateDB Protein IDBP-691791.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IDI1
Protein Name Isopentenyl-diphosphate Delta-isomerase 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000005323
InnateDB Gene IDBG-639612 (IDI1)
Protein Structure
UniProt Annotation
Function Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). {ECO:0000250}.
Subcellular Localization Peroxisome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004452 isopentenyl-diphosphate delta-isomerase activity
GO:0016787 hydrolase activity
GO:0016853 isomerase activity
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006629 lipid metabolic process
GO:0006694 steroid biosynthetic process
GO:0006695 cholesterol biosynthetic process
GO:0008202 steroid metabolic process
GO:0008203 cholesterol metabolic process
GO:0008299 isoprenoid biosynthetic process
GO:0016126 sterol biosynthetic process
GO:0035634 response to stilbenoid
GO:0050992 dimethylallyl diphosphate biosynthetic process
Cellular Component
GO:0005739 mitochondrion
GO:0005777 peroxisome
Protein Structure and Domains
PDB ID
InterPro IPR000086 NUDIX hydrolase domain
IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1
IPR015797 NUDIX hydrolase domain-like
PFAM PF00293
PRINTS
PIRSF PIRSF018427
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q1LZ95
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 514293
UniGene Bt.3764
RefSeq NP_001069127
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AAFC03067960 BC116133
GenPept AAI16134

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca