InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: LIMK1

Summary

InnateDB Protein

IDBP-692197.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LIMK1

Protein Name

LIM domain kinase 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053752

InnateDB Gene

IDBG-639960 (LIMK1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008270	zinc ion binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0016773	phosphotransferase activity, alcohol group as acceptor
GO:0031072	heat shock protein binding
GO:0046872	metal ion binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0006468	protein phosphorylation
GO:0009103	lipopolysaccharide biosynthetic process
GO:0032233	positive regulation of actin filament bundle assembly
GO:0045773	positive regulation of axon extension
GO:0051444	negative regulation of ubiquitin-protein transferase activity
GO:0051496	positive regulation of stress fiber assembly

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005925	focal adhesion
GO:0016020	membrane
GO:0043005	neuron projection

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001478 PDZ domain
IPR001781 Zinc finger, LIM-type
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR010440 Lipopolysaccharide kinase
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714
PF00595
PF13180
PF00412
PF06293

PRINTS

PR00109

PIRSF

SMART

SM00228
SM00132
SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt