InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.18959

Summary

InnateDB Protein

IDBP-692519.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.18959

Protein Name

Lymphocyte activation gene-3

Synonyms

LAG-3;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000045595

InnateDB Gene

IDBG-640276 (BT.18959)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0005515	protein binding
GO:0042289	MHC class II protein binding

Biological Process

GO:0007166	cell surface receptor signaling pathway
GO:0045085	negative regulation of interleukin-2 biosynthetic process
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
GO:0050868	negative regulation of T cell activation

Cellular Component

GO:0009897

external side of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain

PFAM

PRINTS

PIRSF

SMART

SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E1B7C1

UniProt Splice Variant

Entrez Gene

515155

UniGene

Bt.18959

RefSeq

NP_001232878

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB608099 DAAA02014457 DAAA02014458

GenPept

BAJ61117