InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: KDM4A

Summary

InnateDB Protein

IDBP-692674.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KDM4A

Protein Name

lysine (K)-specific demethylase 4A

Synonyms

JMJD2A;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000002687

InnateDB Gene

IDBG-640369 (KDM4A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0031625	ubiquitin protein ligase binding
GO:0035064	methylated histone binding
GO:0046872	metal ion binding
GO:0051864	histone demethylase activity (H3-K36 specific)

Biological Process

GO:0014898	cardiac muscle hypertrophy in response to stress
GO:0016577	histone demethylation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0070544	histone H3-K36 demethylation

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001965 Zinc finger, PHD-type
IPR002999 Tudor domain
IPR003347 JmjC domain
IPR003349 Transcription factor jumonji, JmjN
IPR019787 Zinc finger, PHD-finger

PFAM

PF00567
PF02373
PF08007
PF02375
PF00628

PRINTS

PIRSF

SMART

SM00249
SM00333
SM00558
SM00545

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite