Version 5.4
Bos taurus Protein: SCNN1A
Summary
InnateDB Protein IDBP-692777.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCNN1A
Protein Name amiloride-sensitive sodium channel subunit alpha
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000003413
InnateDB Gene IDBG-640505 (SCNN1A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005272 sodium channel activity
GO:0005515 protein binding
GO:0015280 ligand-gated sodium channel activity
GO:0050699 WW domain binding
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006814 sodium ion transport
GO:0035725 sodium ion transmembrane transport
GO:0050891 multicellular organismal water homeostasis
GO:0055078 sodium ion homeostasis
Cellular Component
GO:0005829 cytosol
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0031514 motile cilium
GO:0034706 sodium channel complex
GO:0060170 ciliary membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001873 Na+ channel, amiloride-sensitive
IPR004724 Epithelial sodium channel
PFAM PF00858
PRINTS PR01078
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N6U5
UniProt Splice Variant
Entrez Gene 282348
UniGene
RefSeq NP_777023
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02014466 DAAA02014467 DAAA02014468 DAAA02014469 DAAA02014470 DAAA02014471 DAAA02014472 DAAA02014473 DAAA02014474 DAAA02014475
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca