InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CACNA1B

Summary

InnateDB Protein

IDBP-693204.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CACNA1B

Protein Name

voltage-dependent N-type calcium channel subunit alpha-1B

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000045932

InnateDB Gene

IDBG-640876 (CACNA1B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005245	voltage-gated calcium channel activity
GO:0005262	calcium channel activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0008331	high voltage-gated calcium channel activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006816	calcium ion transport
GO:0007268	synaptic transmission
GO:0007269	neurotransmitter secretion
GO:0007626	locomotory behavior
GO:0008016	regulation of heart contraction
GO:0008217	regulation of blood pressure
GO:0034765	regulation of ion transmembrane transport
GO:0048265	response to pain
GO:0051924	regulation of calcium ion transport
GO:0055085	transmembrane transport
GO:0070509	calcium ion import
GO:0070588	calcium ion transmembrane transport
GO:0086010	membrane depolarization during action potential

Cellular Component

GO:0005886	plasma membrane
GO:0005891	voltage-gated calcium channel complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030425	dendrite
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

InterPro

IPR002048 EF-hand domain
IPR002077 Voltage-dependent calcium channel, alpha-1 subunit
IPR003915 Polycystic kidney disease type 2 protein
IPR005447 Voltage-dependent calcium channel, N-type, alpha-1 subunit
IPR005821 Ion transport domain
IPR013122 Polycystin cation channel, PKD1/PKD2
IPR014873 Voltage-dependent calcium channel, alpha-1 subunit, IQ domain

PFAM

PF00036
PF13202
PF13405
PF00520
PF08016
PF08763

PRINTS

PR00167
PR01433
PR01631

PIRSF

SMART

SM00054
SM01062

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt