InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MTTP

Summary

InnateDB Protein

IDBP-693240.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MTTP

Protein Name

Microsomal triglyceride transfer protein large subunit

Synonyms

MTP;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000015850

InnateDB Gene

IDBG-640936 (MTTP)

Protein Structure

UniProt Annotation

Function

Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B.

Subcellular Localization

Endoplasmic reticulum lumen {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005319	lipid transporter activity
GO:0005515	protein binding
GO:0008289	lipid binding

Biological Process

GO:0006497	protein lipidation
GO:0006629	lipid metabolic process
GO:0006641	triglyceride metabolic process
GO:0006810	transport
GO:0006869	lipid transport
GO:0042157	lipoprotein metabolic process
GO:0042632	cholesterol homeostasis
GO:0042953	lipoprotein transport