Version 5.4
Homo sapiens Protein: SST
Summary
InnateDB Protein IDBP-69332.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SST
Protein Name somatostatin
Synonyms SMST;
Species Homo sapiens
Ensembl Protein ENSP00000287641
InnateDB Gene IDBG-69330 (SST)
Protein Structure
UniProt Annotation
Function Somatostatin inhibits the release of somatotropin.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0001101 response to acid
GO:0006972 hyperosmotic response
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0007268 synaptic transmission
GO:0007584 response to nutrient
GO:0007586 digestion
GO:0008285 negative regulation of cell proliferation
GO:0008628 hormone-mediated apoptotic signaling pathway
GO:0009408 response to heat
GO:0010243 response to organonitrogen compound
GO:0030334 regulation of cell migration
GO:0042493 response to drug
GO:0043200 response to amino acid
GO:0048545 response to steroid hormone
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID
InterPro IPR004250 Somatostatin
IPR018142 Somatostatin/Cortistatin, C-terminal
PFAM PF03002
PRINTS
PIRSF PIRSF001814
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P61278
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 6750
UniGene
RefSeq NP_001039
HUGO HGNC:11329
OMIM 182450
CCDS CCDS3288
HPRD 08920
IMGT
EMBL AK312177 BC032625 CH471052 J00306
GenPept AAA60566 AAH32625 BAG35110 EAW78145

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca